by J. Larry Jameson, Anthony S. Fauci, Dennis L. Kasper, Stephen L. Hauser, Dan L. Longo, Joseph Loscalzo
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MASTER MODERN MEDICINE!
Introducing the Landmark Twentieth Edition of the Global Icon of Internal Medicine
The definitive guide to internal medicine is more essential than ever with the latest in disease mechanisms, updated clinical trial results and recommended guidelines, state-of-the art radiographic images, therapeutic approaches and specific treatments, hundreds of demonstrative full-color drawings, and practical clinical decision trees and algorithms
Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine, Harrison’s Principles of Internal Medicine gives you the informational foundation you need to provide the best patient care possible.
Essential for practice and education, the landmark 20th Edition features:
Thoroughly revised content―covering the many new breakthroughs and
advances in clinical medicine that have occurred since the last edition
of Harrison’s. Chapters on acute and chronic hepatitis, management of
diabetes, immune-based therapies in cancer, multiple sclerosis,
cardiovascular disease, HIV, and many more, deliver the very latest
information on disease mechanisms, diagnostic options, and the specific
treatment guidance you need to provide optimal patient care.
State-of-the-art coverage of disease mechanisms: Harrison’s focuses on
pathophysiology with rigor, and with the goal of linking disease
mechanisms to treatments. Improved understanding of how diseases develop
and progress not only promotes better decision-making and higher value
care, but also makes for fascinating reading and improved retention.
Harrison’s summarizes important new basic science developments, such as
the role of mitochondria in programmed and necrotic cell death, the
immune system’s role in cancer development and treatment, the impact of
telomere shortening in the aging and disease processes, and the role of
the microbiome in health and disease. Understanding the role of
inflammation in cardiovascular disease, the precise mechanisms of immune
deficiency in HIV/AIDS, prions and misfolded proteins in
neurodegenerative diseases, and obesity as a predisposition to diabetes
are just a few examples of how this edition provides essential
pathophysiology information for health professionals.
All-new sections covering a wide range of new and emerging areas of
vital interest to all healthcare professionals. New sections include:
Sex and Gender-based Issues in Medicine; Obesity, Diabetes Mellitus, and
Metabolic Syndrome; and Consultative Medicine― Plus, a new Part
covering cutting-edge topics in research and clinical medicine includes
great new chapters on the role of Epigenetics in Health and Disease,
Behavioral Strategies to Improve Health, Genomics and Infectious
Diseases, Emerging Neuro-Therapeutic Technologies, and Telomere Function
in Health and Disease, and Network System Medicine.
Important and timely new chapters―such as Promoting Good Health, LGBT
Health, Systems of Healthcare, Approach to Medical Consultation,
Pharmacogenomics, Antimicrobial Resistance, Worldwide Changes in
Patterns of Infectious Diseases, Neuromyelitis Optica, and more―offer
the very latest, definitive perspectives on must-know topics in medical
education and practice.
Updated clinical guidelines, expert opinions, and treatment approaches
from renowned editors and authors contribute to the accuracy and
immediacy of the text material and present a clear blueprint for
optimizing patient outcomes.
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